Nephrotoxicity with sirolimus
February 16th, 2010
While sirolimus has been thought to be a safer immunosuppressant than cyclosporine or tacrolimus from the point of view of nephrotoxicity. This AJKD study suggests otherwise, with an increased risk of low-grade proteinuria and tubular damage.
Tubular toxicity in sirolimus- and cyclosporine-ba… [Am J Kidney Dis. 2010] – PubMed result.